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Wpływ erytropoetyny na telomerazę w komórkach nowotworowych

Wpływ erytropoetyny na telomerazę w komórkach nowotworowych

Gil Kanfer / Meir Lahav / Orit Uziel

71,96 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630477443
71,96 €
IVA incluido
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Badanie opisane w niniejszej publikacji przedstawia wpływ erytropoetyny na aktywność i regulację telomerazy w komórkach nowotworowych oraz niezłośliwych komórkach nieerytroidalnych. Ekspozycja na erytropoetynę powoduje zwiększenie aktywności telomerazy na poziomie potranslacyjnym poprzez oś Lyn/SRC-AKT. Hamowanie telomerazy, które skraca telomery, znosi ten efekt, co sugeruje, że leczenie erytropoetyną można łączyć ze stosowaniem związków antytelomerazowych w celu zminimalizowania zwiększonej aktywności telomerazy w komórkach nowotworowych.

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