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Os efeitos da eritropoietina na telomerase em células malignas

Os efeitos da eritropoietina na telomerase em células malignas

Gil Kanfer / Meir Lahav / Orit Uziel

71,96 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630480009
71,96 €
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O estudo descrito neste livro apresenta os efeitos da eritropoietina na atividade e regulação da telomerase em células malignas e não malignas não eritroides. A exposição à eritropoietina regula positivamente a atividade da telomerase a nível pós-traducional através do eixo Lyn/SRC-AKT. A inibição da telomerase, que encurta os telómeros, anulou esse efeito, sugerindo que o tratamento com eritropoietina poderia ser administrado em conjunto com compostos anti-telomerase, a fim de minimizar o aumento da atividade da telomerase nas células cancerosas.

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