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Gli effetti dell’eritropoietina sulla telomerasi nelle cellule maligne

Gli effetti dell’eritropoietina sulla telomerasi nelle cellule maligne

Gil Kanfer / Meir Lahav / Orit Uziel

71,96 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630472325
71,96 €
IVA incluido
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Lo studio descritto in questo libro illustra gli effetti dell’eritropoietina sull’attività e sulla regolazione della telomerasi nelle cellule maligne e non maligne non eritroidi. L’esposizione all’eritropoietina aumenta l’attività della telomerasi a livello post-traduzionale attraverso l’asse Lyn/SRC-AKT. L’inibizione della telomerasi, che accorcia i telomeri, ha annullato tale effetto, suggerendo che il trattamento con eritropoietina potrebbe essere somministrato in combinazione con composti anti-telomerasi per ridurre al minimo l’aumento dell’attività della telomerasi nelle cellule tumorali.

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