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Les effets de l’érythropoïétine sur la télomérase dans les cellules malignes

Les effets de l’érythropoïétine sur la télomérase dans les cellules malignes

Gil Kanfer / Meir Lahav / Orit Uziel

72,02 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630469769
72,02 €
IVA incluido
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Sobre IBD

L’étude décrite dans cet ouvrage présente les effets de l’érythropoïétine sur l’activité et la régulation de la télomérase dans des cellules malignes et non malignes non érythroïdes. L’exposition à l’érythropoïétine entraîne une régulation à la hausse de l’activité de la télomérase au niveau post-traductionnel par l’intermédiaire de l’axe Lyn/SRC-AKT. L’inhibition de la télomérase, qui raccourcit les télomères, a annulé cet effet, ce qui suggère que le traitement par l’érythropoïétine pourrait être associé à des composés anti-télomérase afin de minimiser la régulation à la hausse de la télomérase dans les cellules cancéreuses.

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