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Variantes genéticas do recetor scavenger da classe B, tipo I

Variantes genéticas do recetor scavenger da classe B, tipo I

Katharina Winter

72,02 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Ciencia: cuestiones generales
ISBN:
9786630352993
72,02 €
IVA incluido
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Sobre IBD

O recetor scavenger da classe B, tipo I (SR-BI), desempenha um papel central no metabolismo das lipoproteínas de alta densidade (HDL). O seu papel fundamental na captação de colesterol e no transporte reverso de colesterol (RCT) foi confirmado em vários estudos realizados em ratos. O papel do SR-BI nos seres humanos ainda não é claro. Foi identificada uma mutação missense recentemente descrita do SR-BI (P297S) em doentes com níveis elevados de colesterol HDL. O nosso objetivo foi investigar a influência desta mutação na interação entre o SR-BI e o HDL.

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