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Potenziale osteogenico e adipogenico delle cellule staminali mesenchimali

Potenziale osteogenico e adipogenico delle cellule staminali mesenchimali

Rodrigo Paolo Abuna

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786209143397
53,66 €
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Le cellule staminali mesenchimali derivate dal midollo osseo (CTMs-MO) e dal tessuto adiposo (CTMs-TA) sono uno strumento interessante per la riparazione del tessuto osseo basata sulla terapia cellulare. Nel presente studio è stato studiato il potenziale osteogenico e adipogenico delle CTM-MO e delle CTM-TA, nonché l’effetto dell’intercomunicazione tra osteoblasti e adipociti sull’espressione del fenotipo cellulare. È stato evidenziato che le CTM-MO sono più osteogeniche, mentre le CTM-TA sono più adipogeniche. Inoltre, è stato osservato che l’intercomunicazione tra osteoblasti e adipociti può influire negativamente sulla riparazione ossea. Pertanto, ipotizziamo che il maggiore potenziale osteogenico delle CTM-MO le renda la scelta più appropriata per l’induzione della riparazione ossea basata sulla terapia cellulare.

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