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Osteogenes und adipogenes Potenzial mesenchymaler Stammzellen

Osteogenes und adipogenes Potenzial mesenchymaler Stammzellen

Rodrigo Paolo Abuna

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786209168987
53,73 €
IVA incluido
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Mesenchymale Stammzellen aus dem Knochenmark (BM-MSCs) und aus Fettgewebe (AD-MSCs) sind ein attraktives Instrument für die Reparatur von Knochengewebe auf der Grundlage der Zelltherapie. In der vorliegenden Studie wurden das osteogene und adipogene Potenzial von MCS-BM und MCS-WF sowie die Auswirkungen der Interkommunikation zwischen Osteoblasten und Adipozyten auf die Expression des Zellphänotyps untersucht. Es zeigte sich, dass MCS-BM eher osteogen sind, während MCS-WF eher adipogen sind. Darüber hinaus wurde beobachtet, dass die Interkommunikation zwischen Osteoblasten und Adipozyten die Knochenreparatur negativ beeinflussen kann. Daher gehen wir davon aus, dass das größere osteogene Potenzial von CTMs-MO diese zur geeigneteren Wahl für die Induktion der zellbasierten Knochenreparatur macht.

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