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Potentiel ostéogénique et adipogénique des cellules souches mésenchymateuses

Potentiel ostéogénique et adipogénique des cellules souches mésenchymateuses

Rodrigo Paolo Abuna

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786209166426
53,79 €
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Les cellules souches mésenchymateuses dérivées de la moelle osseuse (CTMs-MO) et du tissu adipeux (CTMs-TA) constituent un outil intéressant pour la réparation des tissus osseux basée sur la thérapie cellulaire. Dans la présente étude, nous avons étudié le potentiel ostéogénique et adipogénique des CTM-MO et des CTM-TA, ainsi que l’effet de l’intercommunication entre les ostéoblastes et les adipocytes sur l’expression du phénotype cellulaire. Il a été démontré que les CTM-MO sont plus ostéogéniques, tandis que les CTM-TA sont plus adipogéniques. De plus, il a été observé que l’intercommunication entre les ostéoblastes et les adipocytes peut avoir un effet négatif sur la réparation osseuse. Nous postulons donc que le potentiel ostéogénique plus élevé des CTM-MO en fait le choix le plus approprié pour l’induction de la réparation osseuse basée sur la thérapie cellulaire.

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