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Nuove scoperte sul ruolo della melatonina e del deidroepiandrosterone

Nuove scoperte sul ruolo della melatonina e del deidroepiandrosterone

Abdel-Mohsen Soliman / Hanan Farouk Aly / Hoda El-Sayed Mohamed

129,99 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630201420
129,99 €
IVA incluido
Disponible

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Sobre IBD

Il trattamento con melatonina e/o DHEA ha mostrato effetti terapeutici con percentuali di miglioramento variabili in tutti i parametri biochimici esaminati, grazie a una rigenerazione epatica notevolmente accelerata dopo epatectomia parziale, attraverso l’attenuazione del danno epatico indotto dal DMN grazie alle loro attività di eliminazione dei ROS, la modulazione del danno epatico e della fibrosi epatica mediante l’inibizione delle citochine infiammatorie e dello stress ossidativo, nonché la stimolazione della mitosi degli epatociti, che di conseguenza ha portato alla sopravvivenza dei ratti ad alto rischio di insufficienza epatica postoperatoria dopo l’epatectomia. Questi risultati hanno confermato le attività di eliminazione dei radicali liberi e le proprietà antiossidanti di entrambi i farmaci nel potenziamento della rigenerazione epatica dopo epatectomia parziale, nella cirrosi indotta dal DMN e nel fegato cirrotico sottoposto a epatectomia parziale.

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