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Neue Erkenntnisse zur Rolle von Melatonin und Dehydroepiandrosteron

Neue Erkenntnisse zur Rolle von Melatonin und Dehydroepiandrosteron

Abdel-Mohsen Soliman / Hanan Farouk Aly / Hoda El-Sayed Mohamed

129,96 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786630242386
129,96 €
IVA incluido
Disponible

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Sobre IBD

Die Behandlung mit Melatonin und/oder DHEA zeigte therapeutische Wirkungen mit schwankenden Prozentsätzen der Verbesserung bei allen untersuchten biochemischen Parametern, und zwar durch eine deutlich beschleunigte Leberregeneration nach partieller Hepatektomie, durch ihre ROS-Fänger-Aktivität eine Abschwächung der DMN-induzierten Leberschädigung bewirkte, durch die Hemmung entzündlicher Zytokine und von oxidativem Stress die Leberschädigung und Leberfibrose modulierte sowie die Mitosen der Hepatozyten anregte, was folglich zum Überleben von Ratten mit einem hohen Risiko für ein postoperatives Leberversagen nach einer Hepatektomie führte. Diese Ergebnisse bestätigten die Radikalfänger- und antioxidativen Eigenschaften beider Wirkstoffe bei der Förderung der Leberregeneration nach partieller Hepatektomie, bei DMN-induzierter Zirrhose sowie bei zirrhotischer, partiell hepatektomierter Leber.

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