Mutazioni genetiche nell’artrite reumatoide giovanile

Mutazioni genetiche nell’artrite reumatoide giovanile

Shahin Asadi / Zahra Gholizadeh

72,08 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Genética (no médica)
ISBN:
9786630222265
72,08 €
IVA incluido
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Oggi, le malattie reumatoidi, che colpiscono persone in tutto il mondo, in particolare gli adolescenti, hanno assunto proporzioni epidemiche. La disfunzione del sistema immunitario umano può aumentare la gravità e la frequenza dell’insorgenza della malattia. Pertanto, una diagnosi tempestiva e l’individuazione di eventuali anomalie genetiche associate alle malattie reumatoidi potrebbero alleviare le sofferenze dei giovani pazienti e ridurre la gravità della malattia. In questo libro sono state esaminate le mutazioni del gene HLA-DBR1 nell’ambito dell’artrite reumatoide giovanile nella città di Tabriz, in Iran. Ci auguriamo che i risultati di questa ricerca possano rappresentare un passo avanti verso l’individuazione di un trattamento adeguato per l’artrite reumatoide. L’artrite idiopatica infantile, la malattia reumatica più comune nei neonati, presenta una prevalenza variabile a seconda delle diverse aree geografiche, in base ai criteri utilizzati. In questo progetto sono stati valutati gli alleli HLA-DRB1 in 57 bambini affetti da artrite reumatoide giovanile a Tabriz. Sono stati confrontati i campioni di sangue periferico prelevati da 57 bambini affetti da artrite reumatoide e da 100 giovani sani, utilizzati come gruppo di controllo, per quanto riguarda la preparazione e la presenza degli alleli HLA-DRB1.

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