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Masquage du goût et formulation de comprimés bucco-dispersibles d’ondansétron

Masquage du goût et formulation de comprimés bucco-dispersibles d’ondansétron

Bhupendra Kumar Poudel / Panna Thapa / Shyam Raj Subdei

67,11 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Farmacología
ISBN:
9786209470455
67,11 €
IVA incluido
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Sobre IBD

Le présent travail consiste en une tentative de conception de comprimés bucco-dispersibles d’ondansétron chlorhydrate. Le complexe résine-médicament a été formulé par compression directe en comprimés bucco-dispersibles à l’aide de cellulose microcristalline PH 102 comme diluant et de croscarmellose sodique et d’amidon glycolate sodique comme superdésintégrants, tandis que l’aspartame a été utilisé comme édulcorant pour améliorer le goût. Le masquage du goût a été réalisé à l’aide de la résine polacrilex Tulsion 335. La formulation préparée peut être utile pour les patients qui ont des difficultés à avaler.

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