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Mascaramento do sabor e formulação de comprimidos de ondansetrona para dissolução na boca

Mascaramento do sabor e formulação de comprimidos de ondansetrona para dissolução na boca

Bhupendra Kumar Poudel / Panna Thapa / Shyam Raj Subdei

67,11 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Farmacología
ISBN:
9786209425998
67,11 €
IVA incluido
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Sobre IBD

O presente trabalho é uma tentativa de conceber comprimidos de cloridrato de ondansetrona para dissolução na boca. O complexo de resina do fármaco foi formulado por compressão direta em comprimidos orodispersíveis utilizando celulose microcristalina PH 102 como diluente e croscarmose sódica e glicolato de amido sódico como superdesintegrantes, enquanto o aspartame foi utilizado como adoçante para melhorar a palatabilidade. A máscara de sabor foi feita utilizando resina polacrilex Tulsion 335. A formulação preparada pode ser útil para pacientes com dificuldade em engolir.

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