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Małopłytkowość wywołana heparyną

Małopłytkowość wywołana heparyną

Fatma Thameur / Wided Maatamri

91,01 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786208986742
91,01 €
IVA incluido
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Sobre IBD

Trombocytopenia indukowana heparyną jest złożonym stanem kliniczno-biologicznym związanym z terapią heparyną, prawdziwym standardem przeciwzakrzepowym i paradoksalnie odpowiedzialnym za poważny stan prozakrzepowy. Stanowi ona najpoważniejsze jatrogenne powikłanie terapii heparyną, które musi być wcześnie zdiagnozowane i skutecznie leczone. Postępowanie z nią stanowi prawdziwy nagły przypadek terapeutyczny, wymagający zastosowania nieheparynowych leków przeciwzakrzepowych, takich jak danaparoid sodu i bezpośrednie inhibitory trombiny, mające na celu zahamowanie nadkrzepliwości wywołanej wybuchowym wytwarzaniem trombiny. Diagnostyka biologiczna może być czasami trudna, pomimo postępu w zrozumieniu mechanizmu choroby i rozwoju testów immunologicznych i funkcjonalnych, które mają wiele zalet. Jednym z najskuteczniejszych testów funkcjonalnych jest test uwalniania serotoniny znakowanej radioaktywnie (RAS), który historycznie był uważany za test referencyjny.

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