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L’effetto fisiologico degli ormoni incretina

L’effetto fisiologico degli ormoni incretina

Mehrevan Abd El-moniem / Nadia Mohamed Ahmed

93,43 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Empresa y gestión
ISBN:
9786209428357
93,43 €
IVA incluido
Disponible

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Sobre IBD

Le incretine sono ormoni rilasciati dall’intestino in risposta all’ingestione di nutrienti che potenziano la secrezione di insulina stimolata dal glucosio. La ricerca delle incretine è stata stimolata dall’osservazione che la somministrazione di un carico orale di glucosio porta a una stimolazione della risposta insulinica molto maggiore rispetto a quella ottenuta quando il glucosio viene infuso per via endovenosa per ottenere livelli identici di glucosio nel sangue . Questa differenza tra i due modi di somministrazione del glucosio è stata attribuita agli ormoni incretina, al peptide-1 simile al glucagone (GLP-1) e al polipeptide insulinotropico dipendente dal glucosio (GIP), coinvolti nello smaltimento del glucosio assorbito, attraverso la stimolazione della secrezione di insulina. Infatti, gli agonisti del GLP-1R e gli inibitori della DPP-4 sono stati ampiamente e con successo utilizzati come agenti terapeutici nella gestione del diabete di tipo 2.

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