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Fizjologiczne działanie hormonów inkretynowych

Fizjologiczne działanie hormonów inkretynowych

Mehrevan Abd El-moniem / Nadia Mohamed Ahmed

67,24 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Empresa y gestión
ISBN:
9786209505126
67,24 €
IVA incluido
Disponible

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Sobre IBD

Inkretyny to hormony uwalniane z jelit w odpowiedzi na spożycie składników odżywczych, które wzmacniają stymulowane glukozą wydzielanie insuliny. Poszukiwania inkretyn zostały zainicjowane przez obserwację, że podanie doustnej dawki glukozy prowadzi do znacznie większej stymulacji odpowiedzi insulinowej niż ta uzyskana po dożylnym podaniu glukozy w celu uzyskania identycznego poziomu glukozy we krwi . Różnicę między tymi dwoma sposobami podawania glukozy przypisuje się hormonom inkretynowym, peptydowi glukagonopodobnemu 1 (GLP-1) i glukozozależnemu polipeptydowi insulinotropowemu (GIP), które biorą udział w usuwaniu wchłoniętej glukozy poprzez stymulację wydzielania insuliny. Agoniści GLP-1R i inhibitory DPP-4 są szeroko stosowanymi i skutecznymi środkami terapeutycznymi w leczeniu cukrzycy typu 2.

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