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Identifizierung und Charakterisierung neuer natürlicher NF-κb-Inhibitoren

Identifizierung und Charakterisierung neuer natürlicher NF-κb-Inhibitoren

Muhammad Ishaq

92,19 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209420559
92,19 €
IVA incluido
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Sobre IBD

Der Nuklearfaktor-κB (NF-κB) ist eine Familie von Transkriptionsfaktoren, die eine Reihe von Genen modulieren, die mit Entzündungs- und Immunreaktionen in Verbindung stehen. Die unvermeidliche NF-κB-Aktivierung ist am pathogenen Prozess verschiedener Krankheiten wie Entzündungen und Krebs beteiligt. Die NF-κB-Signalübertragung in Krebszellen ist an der Zellproliferation, der Angiogenese, der Invasion, der Metastasierung, der Entwicklung von Arzneimittelresistenz und der Antiapoptose beteiligt. Ziel der vorliegenden Studie war es, mithilfe einer molekularen Docking-Studie potente NF-kB-Inhibitoren zu identifizieren.

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