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Identificação e caracterização de novos inibidores naturais de NF-κb

Identificação e caracterização de novos inibidores naturais de NF-κb

Muhammad Ishaq

92,12 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209428234
92,12 €
IVA incluido
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Sobre IBD

O fator nuclear-κB (NF-κB) representa uma família de factores de transcrição, que modulam um conjunto de genes associados a respostas inflamatórias e imunitárias. A ativação inevitável do NF-κB envolve o processo patogénico de várias doenças, como a inflamação e o cancro. A sinalização do NF-κB em células cancerosas está envolvida na proliferação celular, angiogénese, invasão, metástases, desenvolvimento de resistência a fármacos e anti-apoptose. O presente estudo teve como objetivo identificar inibidores potentes do NF-kB através de um estudo de acoplamento molecular.

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