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Identificazione e caratterizzazione di nuovi inibitori naturali di NF-κb

Identificazione e caratterizzazione di nuovi inibitori naturali di NF-κb

Muhammad Ishaq

92,12 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209423116
92,12 €
IVA incluido
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Sobre IBD

Il fattore nucleareκB (NF-κB) rappresenta una famiglia di fattori di trascrizione che modula una serie di geni associati alle risposte infiammatorie e immunitarie. L’attivazione inevitabile di NF-κB coinvolge il processo patogenetico di varie malattie come l’infiammazione e il cancro. La segnalazione di NF-κB nelle cellule tumorali è coinvolta nella proliferazione cellulare, nell’angiogenesi, nell’invasione, nelle metastasi, nello sviluppo della resistenza ai farmaci e nell’anti-apoptosi. Il presente studio si proponeva di identificare potenti inibitori di NF-kB mediante uno studio di docking molecolare.

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