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Charakterystyka in vitro i różnicowanie komórek IPS myszy

Charakterystyka in vitro i różnicowanie komórek IPS myszy

Max-Philipp Lentzen

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Ciencia: cuestiones generales
ISBN:
9786208983345
89,45 €
IVA incluido
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Sobre IBD

Przedstawiona praca należy postrzegać w kontekście różnorodnych działań badawczych mających na celu znalezienie i ewentualne wdrożenie odpowiedniej terapii zastępczej komórkami w przypadku strukturalnych chorób mięśnia sercowego. Indukowane pluripotencjalne komórki macierzyste, które w znacznym stopniu nie różnią się od embrionalnych komórek macierzystych i mogą być różnicowane w kardiomiocyty, stanowią w tym przypadku zasadniczą możliwość. Zadaniem było scharakteryzowanie mysich indukowanych pluripotencjalnych komórek macierzystych w porównaniu z embrionalnymi komórkami macierzystymi, zróżnicowanie ich w kardiomiocyty i scharakteryzowanie tych ostatnich. Ponadto należało przeprowadzić selekcję kardiomiocytów za pomocą antybiotyków i ich oczyszczenie za pomocą barwnika fluorescencyjnego.

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