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Caracterização in vitro e diferenciação de células IPS de ratos

Caracterização in vitro e diferenciação de células IPS de ratos

Max-Philipp Lentzen

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Ciencia: cuestiones generales
ISBN:
9786208983390
89,45 €
IVA incluido
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Sobre IBD

O trabalho apresentado deve ser visto no contexto das diversas atividades de investigação destinadas a encontrar e, se necessário, estabelecer uma terapia de substituição celular adequada para doenças estruturais do miocárdio. As células estaminais pluripotentes induzidas, que não diferem significativamente das células estaminais embrionárias e podem ser diferenciadas em cardiomiócitos, representam uma possibilidade fundamental neste contexto. A tarefa consistia em caracterizar células estaminais pluripotentes induzidas murinas em comparação com células estaminais embrionárias, diferenciá-las em cardiomiócitos e caracterizá-las. Além disso, deveria ser realizada uma seleção antibiótica dos cardiomiócitos e sua purificação por meio de um corante fluorescente.

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