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Zjadliwość Candida tropicalis

Zjadliwość Candida tropicalis

G. Hermann Jonas TAPSOBA

51,75 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786208624675
51,75 €
IVA incluido
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Candida tropicalis jest jednym z najbardziej rozpowszechnionych niealbicansowych gatunków C. na świecie (od 3 do 66% izolatów). Celem badania była ocena zjadliwości in vivo tellurycznego szczepu C. tropicalis w oparciu o model G. mellonella. Badanie zostało przeprowadzone w Burkina Faso.Było to prospektywne badanie eksperymentalne. Wykorzystano partie 10 larw o masie od 280 do 320 mg oraz telluryczny szczep C. tropicalis zidentyfikowany metodą MALDI-TOF. Larwy zaszczepiono 20 μl zawiesiny grzybów w rosnących stężeniach 5 105, 1 106 i 5 106 CFU. Grupie kontrolnej wstrzyknięto 20 μl sterylnego PBS. Melanizację i śmierć larw obserwowano po 24 godzinach w ciągu 12 dni.Łącznie 100% larw uległo melanizacji 30 minut po inokulacji w stężeniach 1 106 i 5 106 CFU/larwę, a śmiertelność wyniosła 100% w H48 (p

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