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Virulenza di Candida tropicalis

Virulenza di Candida tropicalis

G. Hermann Jonas TAPSOBA

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786208624682
51,75 €
IVA incluido
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Candida tropicalis è una delle specie di C. non albicans più temute al mondo (dal 3 al 66% degli isolati). Lo scopo dello studio è stato quello di valutare la virulenza in vivo di un ceppo tellurico di C. tropicalis basato sul modello di G. mellonella. Lo studio è stato condotto in Burkina Faso.Si è trattato di uno studio sperimentale prospettico. Sono stati utilizzati lotti di 10 larve da 280 a 320 mg e un ceppo tellurico di C. tropicalis identificato mediante MALDI-TOF. Le larve sono state inoculate con 20μl di sospensione fungina a concentrazioni crescenti di 5.105, 1.106 e 5.106 UFC. Un gruppo di controllo è stato iniettato con 20μl di PBS sterile. La melanizzazione e la morte larvale sono state osservate a 24 ore per 12 giorni.In totale, il 100% delle larve ha melanizzato 30 minuti dopo l’inoculazione a concentrazioni di 1.106 e 5.106 UFC/larva e la mortalità è stata del 100% a H48 (p

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