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Virulenz von Candida tropicalis

Virulenz von Candida tropicalis

G. Hermann Jonas TAPSOBA

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Biologia, ciencias de la vida
ISBN:
9786208624644
51,82 €
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Candida tropicalis ist eine der gefürchtetsten C. non albicans-Arten der Welt (3-66% der Isolate). Ziel der Studie war es, die In-vivo-Virulenz eines tellurischen Stammes von C. tropicalis nach dem Vorbild von G. mellonella zu bewerten. Die Studie wurde in Burkina Faso durchgeführt.Es handelte sich um eine prospektive experimentelle Studie. Es wurden Chargen von 10 Larven mit einem Gewicht von 280 bis 320 mg und ein mit MALDI-TOF identifizierter bodenständiger Stamm von C. tropicalis verwendet. Die Larven wurden mit 20μl Pilzsuspension in ansteigenden Konzentrationen von 5.105, 1.106, und 5.106 KBE geimpft. Eine Kontrollgruppe wurde mit 20μL sterilem PBS-Puffer injiziert. Die Melanisierung und der Tod der Larven wurden/24H über 12 Tage beobachtet.Insgesamt melanisierten sich 100% der Larven 30 min nach der Inokulation bei Konzentrationen von 1.106, und 5.106 KBE/Larve und die Mortalität betrug 100% in H48 (p

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