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Potencial atual e futuro do sistema de administração de medicamentos gastroretentivos

Potencial atual e futuro do sistema de administração de medicamentos gastroretentivos

Meher Priya Sharma / Sneha Anand / Sonia Narwal

60,64 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208800482
60,64 €
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Sobre IBD

Os sistemas de administração de fármacos gastroretentivos são concebidos para prolongar o tempo de retenção gástrica e permitir a libertação controlada ou sustentada de fármacos. Esta abordagem aumenta a concentração do fármaco no local de destino, melhorando potencialmente a biodisponibilidade e reduzindo a dose necessária. Ao longo das últimas décadas, foram desenvolvidas várias tecnologias, cada uma empregando mecanismos diferentes para prolongar a retenção do fármaco no trato gastrointestinal e otimizar a biodisponibilidade. Foi efectuada uma extensa investigação sobre várias estratégias gastroretentoras, incluindo sistemas flutuantes, mucoadesivos, expansíveis, magnéticos, nanofibrosos, de alta densidade e expansíveis. Este livro explora os avanços nestas tecnologias, o seu significado clínico e os métodos de administração de medicamentos, destacando as suas promissoras aplicações futuras.

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