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Obecny i przyszły potencjał gastroretencyjnego systemu dostarczania leków

Obecny i przyszły potencjał gastroretencyjnego systemu dostarczania leków

Meher Priya Sharma / Sneha Anand / Sonia Narwal

60,58 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208800499
60,58 €
IVA incluido
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Gastroretencyjne systemy dostarczania leków zostały zaprojektowane w celu wydłużenia czasu retencji w żołądku i umożliwienia kontrolowanego lub przedłużonego uwalniania leku. Takie podejście zwiększa stężenie leku w miejscu docelowym, potencjalnie poprawiając biodostępność i zmniejszając wymaganą dawkę. W ciągu ostatnich dziesięcioleci opracowano różne technologie, z których każda wykorzystuje różne mechanizmy przedłużania retencji leku w przewodzie pokarmowym przy jednoczesnej optymalizacji biodostępności. Przeprowadzono szeroko zakrojone badania nad kilkoma strategiami gastroretencji, w tym nad systemami pływającymi, mukoadhezyjnymi, pęczniejącymi, magnetycznymi, nanowłóknistymi, o wysokiej gęstości i rozszerzalnymi. Niniejsza książka bada postępy w tych technologiach, ich znaczenie kliniczne i metody dostarczania leków, podkreślając ich obiecujące przyszłe zastosowania.

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