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Niektóre pochodne pirazoliny jako środki przeciwbakteryjne

Niektóre pochodne pirazoliny jako środki przeciwbakteryjne

Manish Kumar Agrawal / Pankaj Kumar Sonar / Shailendra K. Saraf

53,91 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208974145
53,91 €
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Związki heterocykliczne są dobrze znane ze swojego szerokiego zakresu działania biologicznego, a pirazoliny zajmują wyjątkowe miejsce ze względu na ważne zastosowania farmaceutyczne. Pirazoliny odegrały kluczową rolę w rozwoju teorii chemii heterocyklicznej i są również szeroko stosowane jako środki w syntezie organicznej. Klasyczna synteza proponowanych związków obejmuje katalizowaną zasadą reakcję kondensacji aldolowej ketonów aromatycznych i aldehydów, w wyniku której powstają ketony alfa, beta-nienasycone (chalkony), które następnie ulegają reakcji cyklizacji z hydrazyną, dając 2-pirazoliny.

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