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Alguns derivados da pirazolina como agentes antimicrobianos

Alguns derivados da pirazolina como agentes antimicrobianos

Manish Kumar Agrawal / Pankaj Kumar Sonar / Shailendra K. Saraf

53,91 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208974152
53,91 €
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Os compostos heterocíclicos são bem conhecidos pela sua ampla gama de atividades biológicas, e as pirazolinas ocupam um lugar único devido às suas importantes aplicações farmacêuticas. As pirazolinas têm desempenhado um papel crucial no desenvolvimento da teoria da química heterocíclica e também são amplamente utilizadas como agentes na síntese orgânica. Uma síntese clássica dos compostos propostos envolve a reação de condensação aldólica catalisada por base de cetonas aromáticas e aldeídos para dar cetonas alfa, beta-insaturadas (chalconas), que sofrem uma reação de ciclização subsequente com hidrazinas, produzindo 2-pirazolinas.

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