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Alcuni derivati della pirazolina come agenti antimicrobici

Alcuni derivati della pirazolina come agenti antimicrobici

Manish Kumar Agrawal / Pankaj Kumar Sonar / Shailendra K. Saraf

53,91 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208974138
53,91 €
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I composti eterociclici sono ben noti per la loro ampia gamma di attività biologiche e le pirazoline occupano un posto unico grazie alle loro importanti applicazioni farmaceutiche. Le pirazoline hanno svolto un ruolo cruciale nello sviluppo della teoria della chimica eterociclica e sono anche ampiamente utilizzate come agenti nella sintesi organica. Una sintesi classica dei composti proposti prevede la reazione di condensazione aldolica catalizzata da una base di chetoni aromatici e aldeidi per dare chetoni alfa, beta-insaturi (calconi), che subiscono una successiva reazione di ciclizzazione con idrazine che danno 2-pirazoline.

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