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Le cellule staminali come trattamento promettente per il diabete mellito

Le cellule staminali come trattamento promettente per il diabete mellito

Eman Refaat / Nadia Mohamed Ahmed J. S. Hussein

65,86 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Empresa y gestión
ISBN:
9786209416118
65,86 €
IVA incluido
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Sobre IBD

Le cellule staminali mesenchimali (MSC) rappresentano una terapia promettente nella medicina rigenerativa. Le MSC sono presenti in molti tessuti adulti e fetali, come il midollo osseo, il tessuto adiposo, il sangue del cordone ombelicale e la gelatina di Wharton del cordone ombelicale. Le MSC, con la loro capacità di autorinnovamento e il loro potenziale di transdifferenziazione, sono una fonte cellulare illimitata e interessante per il trattamento dei pazienti diabetici. D’altra parte, le MSC hanno proprietà immunomodulanti ben caratterizzate che possono sopprimere il danno infiammatorio e il rigetto immuno-mediato e, secernendo fattori paracrini e depositando la matrice extracellulare, migliorano l’attecchimento delle isole pancreatiche nella nicchia microambientale. La sostituzione delle isole pancreatiche malate con altre sane e funzionanti provenienti da donatori cadavere è un approccio altamente efficace per il trattamento del diabete insulino-dipendente.

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