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Células estaminais como tratamento promissor para a diabetes mellitus

Células estaminais como tratamento promissor para a diabetes mellitus

Eman Refaat / Nadia Mohamed Ahmed J. S. Hussein

65,86 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Empresa y gestión
ISBN:
9786209423796
65,86 €
IVA incluido
Disponible

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Sobre IBD

As células estaminais mesenquimais (MSC) representam uma terapia promissora na medicina regenerativa. As MSCs estão presentes em muitos tecidos adultos e fetais, tais como a medula óssea, o tecido adiposo, o sangue do cordão umbilical e a geléia de Wharton do cordão umbilical. As MSC, com capacidade de auto-renovação e potencial de transdiferenciação, são uma fonte celular ilimitada e atraente para o tratamento de pacientes diabéticos. Por outro lado, as MSC têm propriedades imunomoduladoras bem caracterizadas que podem suprimir danos inflamatórios e rejeição imunomediada e, através da secreção de fatores parácrinos e deposição da matriz extracelular, melhoram o enxerto de ilhotas pancreáticas em nichos microambientais. A substituição de ilhotas pancreáticas doentes por outras saudáveis e funcionais de doadores cadavéricos é uma abordagem altamente eficaz para tratar a diabetes insulino-dependente.

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