Inicio > Matemáticas y ciencia > Biologia, ciencias de la vida > HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS
HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS

HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS

Kinjal Majithiya / Palak Guralwar / Sonal Manohar

75,58 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Biologia, ciencias de la vida
ISBN:
9786208010676
75,58 €
IVA incluido
Disponible

Selecciona una librería:

  • Librería Samer Atenea
  • Librería Aciertas (Toledo)
  • Kálamo Books
  • Librería Perelló (Valencia)
  • Librería Elías (Asturias)
  • Donde los libros
  • Librería Kolima (Madrid)
  • Librería Proteo (Málaga)
Sobre IBD

Hypoxia is a typical microenvironmental characteristic of many solid tumors. HIF-1 is the key regulator of growing tumor’s response to hypoxia. HIF-1α subunit levels rise in hypoxic environments, when oncogenes are activated, and/or when tumor suppressor genes are inactivated, this is necessary for HIF-1 function in tumors. HIF-1 turns on genes that enable cells of a solid tumor to flourish in the noxious hypoxic tumor environment via attainment of numerous cancer hallmarks. This book elaborates the regulation and role of HIF-1 in oncogenic signalling. Further, its potential as a drug target for solid tumors is also discussed. The book will be useful as a reference book for students of graduate and post-graduate level courses in Life Science, Biomedical Science as well as to those who have a special interest in Cancer Biology.

Artículos relacionados

  • Viral Replication Complexes
    Viruses are obligate intracellular parasites that need to co-opt a living cell’s machinery for replication. At the heart of the viral replication machinery are the nucleic acid polymerases, which are responsible for efficiently copying the viral genome. This process must often be coordinated with other viral processes, including protein translation and viral packaging. The poly...
  • Advances in Flavivirus Research
    The flaviviruses are composed almost entirely of arthropod-borne viruses, a subset of which are responsible for millions of cases of human disease each year. Among these viruses are dengue virus—a scourge throughout the tropical regions of Asia and the Americas; yellow fever virus—the “original” hemorrhagic fever virus; and the recently emerged Zika virus. While the flaviviruse...
    Disponible

    51,85 €

  • Brain Asymmetry of Structure and/or Function
    Lesley J. Rogers / Lesley JRogers
    This edited book brings together research reports on the asymmetry of brain function in various species, including humans, dogs, birds, lizards and bees. As shown in a wide range of species, and, as we now know, not solely in humans, the left and right sides of the brain process information in different ways and control different responses or patterns of behaviour. Since this d...
    Disponible

    51,71 €

  • Fungal Pigments
    With the impact of globalization in research trends, the search for healthier life styles, the increasing public demand for natural, organic, and ‘clean labelled’ products, as well as the growing global market for natural colorants in economically fast-growing countries all over the world, filamentous fungi started to be investigated as readily available sources of chemically d...
    Disponible

    43,80 €

  • The Epithelialto- Mesenchymal Transition ( EMT ) in Cancer
    Joëlle Roche
    The epithelial-to-mesenchymal transition (EMT) is a highly dynamic process with multiple transitional states, by which epithelial cells can convert into a mesenchymal phenotype. This process involves loss of cellular adhesion and cellular polarity, and an improvement in migratory and invasive properties. It occurs during normal embryonic development, tissue regeneration, organ ...
    Disponible

    67,86 €

  • The Biology and Treatment of Myeloid Leukaemias
    There has been an observed decrease in the global mortality from cancer, mostly atributable to improved, particularly early, detection and prevention. For many carcinomas and leukaemias in adults, once the disease has reached a certain stage there are no therapies that are able to erradicate the cancer cells and cure patients. There has been progress in the treatment of acute m...
    Disponible

    51,85 €

Otros libros del autor

  • HIF-1 como potencial alvo de drogas para tumores sólidos
    Kinjal Majithiya / Palak Guralwar / Sonal Manohar
    A hipóxia é uma caraterística microambiental típica de muitos tumores sólidos. O HIF-1 é o principal regulador da resposta do tumor em crescimento à hipóxia. Os níveis da subunidade HIF-1α aumentam em ambientes hipóxicos, quando os oncogenes são activados e/ou quando os genes supressores de tumores são inactivados, o que é necessário para a função do HIF-1 nos tumores. O HIF-1 ...
    Disponible

    75,58 €

  • HIF-1 als potenzielles Medikamentenziel für solide Tumoren
    Kinjal Majithiya / Palak Guralwar / Sonal Manohar
    Hypoxie ist ein typisches Merkmal der Mikroumgebung vieler solider Tumoren. HIF-1 ist der Hauptregulator für die Reaktion des wachsenden Tumors auf Hypoxie. Der Spiegel der HIF-1α-Untereinheit steigt in hypoxischen Umgebungen an, wenn Onkogene aktiviert und/oder Tumorsuppressorgene inaktiviert werden; dies ist für die Funktion von HIF-1 in Tumoren notwendig. HIF-1 schaltet Gene...
    Disponible

    75,64 €

  • HIF-1 comme cible médicamenteuse potentielle pour les tumeurs solides
    Kinjal Majithiya / Palak Guralwar / Sonal Manohar
    L’hypoxie est une caractéristique microenvironnementale typique de nombreuses tumeurs solides. HIF-1 est le régulateur clé de la réponse de la tumeur en croissance à l’hypoxie. Les niveaux de la sous-unité HIF-1α augmentent dans les environnements hypoxiques, lorsque les oncogènes sont activés et/ou lorsque les gènes suppresseurs de tumeurs sont inactivés, ce qui est nécessaire...
    Disponible

    75,64 €

  • HIF-1 come potenziale bersaglio farmacologico per i tumori solidi
    Kinjal Majithiya / Palak Guralwar / Sonal Manohar
    L’ipossia è una caratteristica microambientale tipica di molti tumori solidi. HIF-1 è il regolatore chiave della risposta del tumore in crescita all’ipossia. I livelli della subunità HIF-1α aumentano in ambienti ipossici, quando gli oncogeni sono attivati e/o quando i geni soppressori tumorali sono inattivati, il che è necessario per la funzione di HIF-1 nei tumori. L’HIF-1 att...
    Disponible

    75,58 €