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Effet antifongique de l’extrait d’encre de seiche contre l’aspergillose pulmonaire

Effet antifongique de l’extrait d’encre de seiche contre l’aspergillose pulmonaire

Enas Ali / Nevien Ahmed / Sohair Fahmy

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209503177
67,11 €
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Sobre IBD

L’utilisation généralisée d’antibiotiques, de corticostéroïdes, de médicaments antitumoraux et d’immunosuppresseurs augmente la morbidité de l’aspergillose pulmonaire invasive (API). La sécrétion d’encre des mollusques a été identifiée comme l’une des nouvelles sources de composés bioactifs. La présente étude a démontré une bonne activité antifongique in vitro et in vivo de l’extrait d’encre de seiche (IE) contre Aspergillus fumigatus. Par rapport au groupe IPA, les animaux traités par IE, AMB et AMB + IE ont vu leur charge fongique pulmonaire baisser de 67,80 %, 83,41 % et 72,68 % respectivement. Les résultats des études in vivo et in vitro montrent que l’IE a un effet thérapeutique contre l’aspergillose pulmonaire invasive en réduisant le stress oxydatif.

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