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Efeito antifúngico do extrato de tinta de sépia contra a aspergilose pulmonar

Efeito antifúngico do extrato de tinta de sépia contra a aspergilose pulmonar

Enas Ali / Nevien Ahmed / Sohair Fahmy

67,05 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209510854
67,05 €
IVA incluido
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O uso generalizado de antibióticos, corticosteroides, medicamentos antitumorais e imunossupressores aumenta a morbidade da aspergilose pulmonar invasiva (API). A secreção de tinta de espécies de moluscos foi identificada como uma das novas fontes de compostos bioativos. O presente estudo mostrou uma boa atividade antifúngica in vitro e in vivo do extrato de tinta de sépia (IE) contra o Aspergillus fumigatus. Em comparação com o grupo IPA, os animais tratados com IE, AMB e AMB + IE apresentaram uma redução de 67,80%, 83,41% e 72,68% na carga fúngica pulmonar, respetivamente. Os resultados registrados dos estudos in vivo e in vitro mostram que o IE tem efeito terapêutico contra a aspergilose pulmonar invasiva através da redução do stress oxidativo.

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