Candida albicans

Candida albicans

Anitha Dayakar / Shaila M / Supriya H

66,79 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209676727
66,79 €
IVA incluido
Disponible

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Sobre IBD

Dominujące grzyby izolowane z jamy ustnej człowieka należą do rodzaju Candida i chociaż istnieje ponad 150 gatunków Candida, około tylko 10 z nich kolonizuje jamę ustną. Candida albicans (C. albicans) jest najczęściej rozpoznawanym gatunkiem (70-75% izolatów), a następnie C. glabrata i C. tropicalis (7% izolatów). Szereg czynników, w tym czynniki gospodarza, ogólnoustrojowe i jatrogenne, wiąże się ze wzrostem częstości występowania zakażeń oportunistycznych z udziałem Candida, a zatem uważanych za gatunki patogenne. Przejście tego nieszkodliwego komensala w chorobotwórczego 'pasożyta' może być związane z atrybutami wirulencji mikroorganizmu i szeregiem czynników gospodarza. Czynniki przyczyniające się do patogenności obejmują cząsteczki powierzchniowe, które pośredniczą w adhezji i inwazji do komórek gospodarza, wydzielanie hydrolaz, przejście od drożdży do alfa, wyczuwanie kontaktu i tygmotropizm, tworzenie biofilmu, zmianę fenotypu i szereg atrybutów sprawności. Poniżej przedstawiamy różne sposoby, w jakie ten normalny komensal staje się patogenny, jego możliwe interakcje z komórkami nabłonka gospodarza i rolę w złośliwej transformacji błony śluzowej jamy ustnej.

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