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Wpływ lnu na otyłość i starzenie biologiczne

Wpływ lnu na otyłość i starzenie biologiczne

Ahlem LAISSOUF

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Biologia, ciencias de la vida
ISBN:
9786208412661
104,52 €
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Otyłość wiąże się z zaburzeniami metabolicznymi i intensywnym stresem oksydacyjnym, który może nasilać się wraz z wiekiem. Celem niniejszego badania było sprawdzenie korzystnego wpływu oleju lnianego, który jest bogaty w wielonienasycone kwasy tłuszczowe n-3 (n-3 PUFA), na zaburzenia metabolizmu lipidów i statusu redoks wywołane dietą kafeteryjną (hiperlipidową i hiperkaloryczną) u starszych szczurów wistar. Starzejące się szczury podzielono na sześć grup karmionych kontrolną (standardową) dietą z dodatkiem lub bez oleju lnianego w stężeniu (2,5% lub 5%) oraz pozostałe karmione dietą kafeteryjną z dodatkiem lub bez oleju lnianego w obu stężeniach. Szczury uśmiercono po dwóch miesiącach stosowania diety. Pobrano próbki krwi i narządów (wątroba, tkanka tłuszczowa, mięśnie, jelita) w celu określenia zmian w metabolizmie lipidów i stanie redoks. Wyniki pokazują, że dieta kafeteryjna wywołuje otyłość, hiperglikemię i hiperlipidemię ze zmienionym składem kwasów tłuszczowych w surowicy i narządach u starszych szczurów wistar.

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