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Synteza kilku potencjalnych niesteroidowych leków przeciwzapalnych

Synteza kilku potencjalnych niesteroidowych leków przeciwzapalnych

Biplab Debnath / Prasanta Kumar Sarma / Sudip Kumar Mandal

49,68 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Química
ISBN:
9786208819392
49,68 €
IVA incluido
Disponible

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Sobre IBD

Niesteroidowe leki przeciwzapalne są jedną z powszechnie przepisywanych grup leków na całym świecie i są bardzo skuteczne jako środki przeciwbólowe, przeciwgorączkowe i przeciwzapalne. Jednak ich stosowanie wiąże się również ze zdarzeniami niepożądanymi, takimi jak owrzodzenie żołądka i dwunastnicy oraz krwawienie z przewodu pokarmowego. Zawsze istnieje duża potrzeba opracowania inhibitorów specyficznych dla COX-2, aby uniknąć skutków ubocznych. Niniejszy raport zawiera krótkie wprowadzenie do stanu zapalnego, biosyntezy prostaglandyn z naciskiem na enzymy COX-1 i COX-2. Główny nacisk położono na przegląd literatury dotyczącej pochodnych indanu oraz prace eksperymentalne przeprowadzone w laboratorium w celu opracowania nowszych i mniej wrzodziejących NLPZ.

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