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Sistema di patch gastrointestinali

Sistema di patch gastrointestinali

Pramila Chaubey / Vasanti Suvarna

43,69 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786207885077
43,69 €
IVA incluido
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Sobre IBD

I sistemi di patch gastrointestinali sono emersi come potenziali sistemi di rilascio di farmaci che presentano problemi con i sistemi di rilascio convenzionali. La loro multifunzione integrata potrebbe superare queste sfide fornendo bioadesione, protezione dal farmaco e rilascio unidirezionale. Questa combinazione di funzioni potrebbe migliorare la biodisponibilità orale complessiva di molecole di grandi dimensioni, come proteine e peptidi, che attualmente possono essere somministrate solo per via iniettiva. Inoltre, i sistemi di patch idrogel gated producono complessi modelli di rilascio pulsatile e potrebbero imitare in modo più naturale il modo in cui il corpo produce composti, come l’insulina e alcuni ormoni. Questo rilascio autoregolato e il targeting specifico per le cellule hanno il potenziale per fornire ulteriori caratteristiche impudenti a questa innovativa piattaforma terapeutica.

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