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Sistema de adesivos gastro-intestinais

Sistema de adesivos gastro-intestinais

Pramila Chaubey / Vasanti Suvarna

43,69 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Farmacología
ISBN:
9786207885084
43,69 €
IVA incluido
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Sobre IBD

Os sistemas de adesivos gastrointestinais surgiram como potenciais sistemas de administração de fármacos que enfrentam desafios com os sistemas convencionais de administração de fármacos. A sua multifuncionalidade integrada pode ultrapassar estes desafios, proporcionando bioadesão, proteção contra o fármaco e libertação unidirecional. Esta combinação de funções pode melhorar a biodisponibilidade oral global de grandes moléculas, como proteínas e péptidos, que atualmente só podem ser administradas por injeção. Além disso, o sistema de adesivos de hidrogel com gates produz padrões complexos de libertação pulsátil e pode imitar de forma mais natural a forma como o corpo produz compostos, como a insulina e algumas hormonas. Esta libertação auto-regulada e o direcionamento específico para as células têm o potencial de conferir características adicionais de impulsividade a esta plataforma terapêutica inovadora.

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