Sintesi, spettroscopia, attività biologica di complessi a ligando misto

Sintesi, spettroscopia, attività biologica di complessi a ligando misto

Hanan Okla

98,63 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
ISBN:
9786208806835
98,63 €
IVA incluido
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Un nuovo legante Schiff (HL) derivato dalla condensazione di chinolina-2-carbossaldeide con 2-amminofenolo e i suoi complessi di leganti misti di Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) e Cd(II) con 2,2’-bipiridina/1,10-fenantrolina come ligando secondario sono stati sintetizzati e caratterizzati mediante analisi elementari, studi spettroscopici (IR, spettri di massa, 1H NMR, UV-vis, suscettibilità magnetica e riflettanza solida), conduttanza molare, diffrazione a raggi X, ESR e studi termici. I parametri cinetici e termodinamici sono stati calcolati utilizzando i metodi Coats-Redfern e Horowitz-Metzger. Inoltre, il legante a base di Schiff e i suoi complessi di leganti misti sono stati sottoposti a screening contro i batteri Gram positivi (Streptococcus pneumoniae e Bacillis subtilis) e i batteri Gram negativi (Pseudomonas aeruginosa ed Escherichia coli). È stata inoltre testata l’attività anticancro del legante a base di Schiff e dei suoi complessi di ligandi misti contro la linea cellulare del cancro al seno (MCF-7) e la linea cellulare del cancro al colon (HCT-116).

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