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Role of Capsaicin in Oxidative Stress and Cancer

Role of Capsaicin in Oxidative Stress and Cancer

Sanjay K. Srivastava

135,93 €
IVA incluido
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Editorial:
Springer Nature B.V.
Año de edición:
2015
Materia
Ciencia: cuestiones generales
ISBN:
9789401784290
135,93 €
IVA incluido
Disponible

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Sobre IBD

This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.

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