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Química do Isoxazol

Química do Isoxazol

Mayuri Ravindra Joshi / Nilima Narendra Dixit

65,43 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Química orgánica
ISBN:
9786209002564
65,43 €
IVA incluido
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A química do isoxazol está associada ao nome de Ludwig Claisen, que descobriu a 3-fenil-5-isoxazolona através da reação do éster benzoilacético com a hidroxilamina. As 4-isoxazolonas que são tautoméricas com os 4-hidroxi-isoxazóis têm recebido pouca atenção. O reconhecimento da atividade farmacológica de alguns derivados do isoxazol, como o Cycliton, uma dialquilamida do ácido carboxílico do isoxazol utilizada como analéptico2-4 e a Gantrisina, um medicamento sulfa a partir do amino isoxazol5-8, contribuiu para o desenvolvimento da química dos isoxazóis. O antibiótico Cicloserina9,10 (ou oxamicina), um derivado simples da 3-isoxazolidona, despertou um novo interesse neste domínio.

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Otros libros del autor

  • Chemie von Isoxazol
    Mayuri Ravindra Joshi / Nilima Narendra Dixit
    Die Chemie der Isoxazole ist mit dem Namen von Ludwig Claisen verbunden, der das 3-Phenyl-5-isoxazolon durch die Reaktion von Benzoylessigester mit Hydroxylamin entdeckte. 4-Isoxazolone, die tautomer zu 4-Hydroxy-Isoxazolen sind, wurden bisher wenig beachtet. Die Anerkennung der pharmakologischen Aktivität einiger Isoxazolderivate wie Cycliton, einem Dialkylamid der Isoxazolcar...
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  • Chemistry of Isoxazole
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    The chemistry of isoxazole is associated with the name of Ludwig Claisen who discovered 3-phenyl-5-isoxazolone by carrying out the reaction of benzoyl acetic ester with hydroxylamine. 4-Isoxazolones which are tautomeric with 4-hydroxy-isoxazoles have received little attention. The recognition of the pharmacological activity of some isoxazole derivatives such as Cycliton, a dial...
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