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Niedokrwistość sierpowatokrwinkowa

Niedokrwistość sierpowatokrwinkowa

Sudhir Rawlani

65,43 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Medicina: cuestiones generales
ISBN:
9786209612084
65,43 €
IVA incluido
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Sobre IBD

Niedokrwistość sierpowatokrwinkowa jest dziedziczną chorobą krwi spowodowaną mutacją w genie β-globiny, prowadzącą do powstania nieprawidłowej hemoglobiny zwanej HbS.W warunkach niskiego poziomu tlenu HbS polimeryzuje, powodując, że czerwone krwinki stają się sierpowate, sztywne i kruche.Te nieprawidłowe komórki mają krótką żywotność (10-20 dni) i mogą blokować małe naczynia krwionośne.Kluczowe cechy:Przewlekła niedokrwistość hemolitycznaBolesne kryzysy naczyniowo-okluzyjneNawracające infekcje (z powodu funkcjonalnej asplenii)Opóźniony wzrost i uszkodzenie narządów (śledziona, nerki, płuca, mózg)

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