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Molekularer Nachweis von Leishmania-Parasiten anhand der Gattung Phlebotomus

Molekularer Nachweis von Leishmania-Parasiten anhand der Gattung Phlebotomus

Ilhem Mihoubi / Khalida Frahtia / Stéphane Picot

114,47 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209858642
114,47 €
IVA incluido
Disponible

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Sandmücken spielen eine wichtige Rolle bei menschlichen Erkrankungen wie Leishmaniose. Die von den algerischen Gesundheitsbehörden eingeleitete Vektorkontrolle erweist sich als wirksam, da die Leishmaniose in Algerien offenbar zurückgeht. Vor diesem Hintergrund zielt diese Studie auf den molekularen Nachweis von Leishmania anhand des Vektors ab. Darüber hinaus wurde eine molekulare Diagnose auch an Hautproben durchgeführt, die von Patienten aus der Region Constantine entnommen wurden. Was den Vektor betrifft, so wurden 5858 Sandfliegen gefangen, darunter 4360 Männchen und 1498 Weibchen, verteilt auf 5 Arten. Bei den Hautproben erwiesen sich 56,96 % der entnommenen Proben im RT-PCR-Test als positiv. Was den Nachweis von Leishmanien aus den Sandflöhen mittels PCR betrifft, so zeigen die Ergebnisse, dass 3 von 60 durchgeführten Gattungs-PCR-Tests positiv waren. Dies beweist, dass die Vektoren parasitiert waren; die Identifizierung der Art mittels RT-PCR führte hingegen zu keinem Ergebnis. Dies könnte durch eine unzureichende Menge an Leishmania-DNA im Vektor erklärt werden und somit die Hypothese eines Rückgangs der Leishmaniose in Constantine stützen.

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