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Molecular epidemiology and genetic diversity of noroviruses

Molecular epidemiology and genetic diversity of noroviruses

Elisson Furlan Figueiredo

60,21 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Microbiología (no médica)
ISBN:
9786207724284
60,21 €
IVA incluido
Disponible

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Acute childhood gastroenteritis affects more than 700 million children under the age of five every year and causes approximately 1.87 million deaths, a figure that represents 12% of childhood deaths worldwide. Viral pathogens are among the most common causes of childhood gastroenteritis and norovirus is one of the major causes of sporadic outbreaks of diarrhea in adults and children under five years of age. The aim of this study was to detect and characterize the genetic variability of norovirus in faecal samples from cases of childhood gastroenteritis. Screening was carried out using an enzyme-linked immunosorbent assay and the positive samples were subjected to genotyping by RT-PCR, partial genome sequencing and phylogenetic analysis. A total of 975 fecal samples were analyzed, resulting in 144 (14.7%) positive samples. The prevalence of norovirus was higher than the prevalence of rotavirus (12%), previously characterized in these samples. There was no seasonal pattern related to norovirus infection.

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Otros libros del autor

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  • Epidemiologia molecolare e diversità genetica dei norovirus
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  • Molekulare Epidemiologie und genetische Vielfalt von Noroviren
    Elisson Furlan Figueiredo
    Akute Gastroenteritis im Kindesalter betrifft jedes Jahr mehr als 700 Millionen Kinder unter fünf Jahren und verursacht etwa 1,87 Millionen Todesfälle, was 12 % der weltweiten Todesfälle im Kindesalter entspricht. Virale Erreger gehören zu den häufigsten Ursachen von Gastroenteritis im Kindesalter, und das Norovirus ist eine der Hauptursachen für sporadische Ausbrüche von Durch...
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