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Midazolam-mukohaftende Mikroemulsion zur intranasalen Verabreichung

Midazolam-mukohaftende Mikroemulsion zur intranasalen Verabreichung

Mahmooda Shaik

53,66 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208869212
53,66 €
IVA incluido
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Sobre IBD

Die mukohaftende Mikroemulsion von Midazolam wurde unter Verwendung von Polymer-Chitosan und Ölen mittels Phasentitrationsverfahren erfolgreich hergestellt. Dies fördert die Freisetzung über einen längeren Zeitraum und ermöglicht somit eine einmal tägliche Dosierung. Aus der In-vitro-Freisetzungsstudie wurde geschlossen, dass bei einer Erhöhung oder Verringerung der Chitosan-Konzentration über bzw. unter die optimierte Konzentration die Freisetzungsrate des Wirkstoffs abnahm.

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