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Médicaments antipaludiques à base de plantes

Médicaments antipaludiques à base de plantes

Rakesh Kumar Sharma

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Ciencia: cuestiones generales
ISBN:
9786208250898
43,94 €
IVA incluido
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Le rythme auquel la recherche sur la quinine progresse nous mènera certainement à un régime médicamenteux bénéfique pour le traitement de la malaria. Même si l’utilisation de la quinine et de ses sels n’est pas encore répandue en Inde, des recherches actives sur la culture de tissus, l’activité et la formulation de dérivés puissants comme le sulfate de quinine sont menées. L’introduction de l’artémisinine et de ses dérivés, comparativement plus puissants que la chloroquine, la méfloquine, la quinine, etc. est un aspect encourageant dans ce domaine de l’augmentation de la résistance aux médicaments chez Plasmodium vivax et les études en tant que telles nécessiteraient l’utilisation de ces médicaments. Une étude approfondie sur la polychimiothérapie avec la quinine, l’huile d’artémisinine et d’autres médicaments pourrait réduire l’incidence du développement de souches résistantes à la quinine. Des études cliniques sur les dérivés plus puissants de l’artémisinine ayant des taux de recrudescence faibles et des effets toxiques, ainsi que sur leur formulation, permettraient d’améliorer l’utilisation thérapeutique de ces composés.

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