L’INVASION PÉRINEURALE - LA VOIE SILENCIEUSE DE LA PROPAGATION DU CANCER

L’INVASION PÉRINEURALE - LA VOIE SILENCIEUSE DE LA PROPAGATION DU CANCER

Arushi Chaure / Jaya Joshi

65,55 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209408090
65,55 €
IVA incluido
Disponible

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Ce livre propose une exploration approfondie de l’une des voies de propagation du cancer les plus importantes sur le plan clinique, mais encore sous-estimée.L’invasion périneurale (IPN) est de plus en plus reconnue comme un facteur prédictif indépendant de mauvais pronostic dans de nombreuses tumeurs malignes, en particulier dans les cancers de la tête et du cou, mais sa biologie reste incomplètement comprise.Le livre commence par une définition claire et une perspective historique de l’IPN, retraçant son évolution d’une observation purement morphologique à un processus complexe et biologiquement dirigé. Il détaille les modèles expérimentaux in vitro, ex vivo et in vivo qui ont façonné notre compréhension du mécanisme, y compris les essais de coculture de DRG, les systèmes de matrice 3D, les modèles d’explants nerveux et les modèles d’inoculation du nerf sciatique, en soulignant leurs points forts, leurs limites et leurs applications translationnelles.

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