INWAZJA OKOŁONERWOWA - CICHA ŚCIEŻKA ROZPRZESTRZENIANIA SIĘ RAKA

INWAZJA OKOŁONERWOWA - CICHA ŚCIEŻKA ROZPRZESTRZENIANIA SIĘ RAKA

Arushi Chaure / Jaya Joshi

65,55 €
IVA incluido
Disponible
Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209413216
65,55 €
IVA incluido
Disponible

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Sobre IBD

Ta książka zapewnia dogłębną eksplorację jednej z najbardziej znaczących klinicznie, ale niedocenianych dróg rozprzestrzeniania się raka. Inwazja okołonerwowa (PNI) jest coraz częściej uznawana za niezależny czynnik prognostyczny złego rokowania w wielu nowotworach złośliwych, w szczególności w nowotworach głowy i szyi, ale jej biologia pozostaje niekompletnie poznana. Książka zaczyna się od jasnej definicji i historycznej perspektywy PNI, śledząc jej ewolucję od czysto morfologicznej obserwacji do złożonego, biologicznie napędzanego procesu. Szczegółowo opisuje modele eksperymentalne in vitro, ex vivo i in vivo, które ukształtowały nasze mechanistyczne zrozumienie, w tym testy współhodowli DRG, systemy macierzy 3D, modele eksplantacji nerwów i modele inokulacji nerwu kulszowego, podkreślając ich mocne strony, ograniczenia i zastosowania translacyjne.

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