INVASÃO PERINEURAL - A VIA SILENCIOSA DE PROPAGAÇÃO DO CANCRO

INVASÃO PERINEURAL - A VIA SILENCIOSA DE PROPAGAÇÃO DO CANCRO

Arushi Chaure / Jaya Joshi

65,55 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
ISBN:
9786209410659
65,55 €
IVA incluido
Disponible

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Sobre IBD

A invasão perineural (IPN) é cada vez mais reconhecida como um preditor independente de mau prognóstico em várias neoplasias malignas, em particular nos cancros da cabeça e do pescoço, mas a sua biologia permanece incompletamente compreendida. O livro começa com uma definição clara e uma perspetiva histórica da IPN, traçando a sua evolução de uma observação puramente morfológica para um processo complexo e biologicamente orientado. O livro apresenta em pormenor os modelos experimentais in vitro, ex vivo e in vivo que moldaram a nossa compreensão mecanicista, incluindo ensaios de co-cultura de DRG, sistemas de matrizes 3D, modelos de explantes nervosos e modelos de inoculação do nervo ciático, destacando os seus pontos fortes, limitações e aplicações translacionais.

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